Cardiac-specific Troponin I (cTnI) is a protein found in the heart that elevates with heart attacks. It may be ordered with other biomarkers such as CKMB and Myoglobin for confirmation however Troponin I levels remain elevated for longer periods of time than CKMB (it will remain high for 1-2 weeks following an heart attack). The troponin test is usually ordered when a patient first comes into the emergency room with chest pain then again at 6 and 12 hours. The troponin test is used to help diagnose a heart attack, to detect and evaluate mild to severe heart injury, and to separate it from chest pain that may be due to other causes.
Enzyme Immunoassay, Chemiluminescence
Sandwich Assay, Antibody-Coated Plate
0, 0.4, 1.25, 2.5, 7.5, 20 ng/ml Dried
LoB 0.0304/ LoD 0.0853 ng/ml
Jan 29, 2019 Advisory:
cTnI products (3825-300 and 3875-300) have been re-calibrated for better low-end discrimination with a lower cutoff/ expected range (<0.4 ng/ml vs <1.3) as well as an antibody-coated plate. Please see updated IFU.